ACT Fire & Rescue and ACT Ambulance Service are on scene at a two-vehicle crash on the corner of Brierly Street and Hindmarsh Drive, Weston.
Hindmarsh Drive is closed eastbound towards Woden. Brierly Street is closed westbound from Hindmarsh Drive.
Firefighters are using hydraulic rescue tools to extricate one patient from each vehicle.
Paramedics are on scene to treat patients as they are freed from the vehicles.
ACT Policing are now on scene managing traffic.